Your browser does not support java script. Skip navigation
Loading, please wait  Loading, please wait...

PCSK9 Inhibitors and Hypercholesterolemia

This drug class has only recently been introduced to the market, and many pharmacists may benefit from information they can use about these medicines.  
The purpose of presenting this information is to increase awareness about PCSK9 inhibitors and to make pharmacists more comfortable with using these drugs to manage the health of their cholesterol patients.  The place of PCSK9 inhibitors in cholesterol treatment is discussed relative to other cholesterol-lowering therapies. 



CE Hours


CE Units


Activity Type

  • Knowledge

Target Audience(s)

  • Pharmacists


Disclosure Policy
The disclosure policies of the SIUE School of Pharmacy Office of Continuing Professional Education requires all persons in a position to control content to disclose any relevant financial relationships with commercial interests. If a conflict is identified, the Office of Professional Continuing Education will initiate a process for resolving the conflict.  The existence of relationships does not necessarily imply bias or lessen the value of the activity.  All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.
The persons required to disclose conflicts include all course faculty, the SIUE CPE administrator, all activity planners and all reviewers.  The relevant commercial financial relationships or affiliations must have occured over the past 12 months.

Accreditation Council for Pharmacy Education
Southern Illinois University Edwardsville School of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.  
The participant must provide the correct NABP ePID number/DOB combination in their electronic profile. All CPE evaluations must be completed within 60 days of completing the activity. It is the participant's responsibility to check that their credit records are correct within the 60 day period after completion of the activity.   Log in to CPE Monitor at to view a list of all ACPE-accredited activities you have taken. Any discrepancies must be resolved with the CPE Provider directly and in a timely manner.


Requirements for CE Credit

To receive CE credit, the participant must complete the online pretest, read the monograph in its entirety, complete the online post-test and receive a score of 70% or greater, and complete the online evaluation.


The authors of this module would like to thank Jared Sheley, Terri Poirier, and Walter Siganga for their assistance completing this activity.




This drug class has recently been introduced for treatment of hypocholesterolemia. Pharmacists will benefit from the updated information presented in this activity.  
The goal of this activity is to provide information that will make pharmacists more comfortable with the PCSK9 inhibitors, and reinforce their knowledge about cholesterol management. 


  • Describe normal lipid physiology in humans and also how normal physiology can be disrupted.
  • List the 4 statin-benefit groups outlined in the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults.
  • Explain the Mechanism of Action of PCSK9 Inhibitors, and their effects on lipid levels compared to other drug classes.
  • Describe the role of the two available PCSK9 inhibitors in treating hypercholesterolemia.


Adam Schulte picture

Adam Schulte
Student, SIUE School of Pharmacy

Brief Bio : Adam is a fourth year student at the SIUE School of Pharmacy expecting to graduate in May 2017. Upon graduation, Adam plans on pursuing a residency. His areas of interest include pain management and education.
Disclosure : Adam Schulte has completed and submitted the SIUE School of Pharmacy Continuing Pharmacy Education Form for Disclosure of Potential Conflicts of Interest and none were reported.
Brock Adam Pontious picture

Brock Adam Pontious
PharmD Candidate 2017, SIUE School of Pharmacy

Brief Bio : Brock is currently an APPE student with Southern Illinois University Edwardsville School of Pharmacy class of 2017. After, school he plans to work in community pharmacy helping his neighbors achieve greater health outcomes. Brock is passionate about educating patients, colleagues, and other healthcare providers about innovations in pharmacy.

Activity Number


Release Date: Feb 27, 2017
Credit Expiration Date: Feb 27, 2020

CE Hours